Panteleimon Rompolas

2014 Regional Award Winner — Post-Doc

Panteleimon Rompolas

Current Position:
Assistant Professor, Department of Dermatology

University of Pennsylvania (Previously at Yale University)

Developmental Biology

Recognized for: Contributions to our understanding of tissue development and regeneration, examining hair follicle stem cell behavior and developing a non-invasive imaging technique to follow the fate of stem cells and their progeny over time in live mammals.

Areas of Research Interest and Expertise: Stem Cells, Regenerative Medicine, Skin Biology, Intravital Imaging

Panteleimon Rompolas


PhD, Biology & Biochemistry, University of Connecticut Health Center
MBA, University of Connecticut
BSc, Biology, National and Kapodistrian University of Athens, Greece

Panteleimon Rompolas earned a B.Sc. in Biology from the University of Athens, Greece (2001) and worked as a Laboratory Technologist at Ikonisys Inc. In 2009 he graduated with an M.B.A. in Management and a Ph.D. in Biomedical Science from the University of Connecticut Health Center, where under the supervision of Dr. Stephen M. King he studied the biology of dynein motor proteins in eukaryotic cilia. Dr. Rompolas then joined Dr. Valentina Greco’s laboratory at Yale University School of Medicine where he developed a system that established for the first time the ability to visualize stem cells in their native environment in mammalian skin. His research provided significant new insight into stem cell behavior and the mechanisms that govern skin regeneration. 

Since August 2015, Dr. Rompolas was recruited at the University of Pennsylvania Perelman School of Medicine as an Assistant Professor of Dermatology. Using the hair follicle and epidermis of the mouse skin as genetically amenable systems his Lab is interested in elucidating the biological basis of skin regeneration and to successfully model and study prevalent human skin diseases.

"My goal is to elucidate the biological mechanisms that enable organs in our adult bodies to regenerate and be maintained throughout life. Uncovering the role of stem cells in these processes will help us understand and treat human disease." 

Key Publications:

  1. Deschene E.R., Myung P., Rompolas P., Zito G., Sun T.Y., Taketo M.M.,  Saotome I.& Greco V. β-catenin activation regulates tissue growth via a non-cell autonomous mechanism within the hair stem cell niche. Science. 2014
  2. Rompolas P., Mesa K. and Greco V. Spatial organization within a niche as a determinant of stem cell fate. Nature. 2013
  3. Rompolas P., Deschene E.R., Zito G.,Gonzalez D., Saotome I., Haberman A. & Greco V. Live imaging of stem cell and progeny behavior in physiological hair-follicle regeneration. Nature. 2012

Other Honors:

2013 Merton Bernfield Memorial Award, the American Society for Cell Biology
(Present) New York Stem Cell Foundation – Druckenmiller Fellow

In the Media:

Looking Below the Surface: Stem Cell Behavior in Real Time. Yale University. Jun 28, 2012